Showing posts with label modafinil. Show all posts
Showing posts with label modafinil. Show all posts

24 January 2016

Drug & Alcohol Facts Week: What teens need to know about caffeine, smart drugs, sleeping pills and melatonin

This week is the National Drug & Alcohol Facts Week℠ (NDAFW), a national health observance for teens which uses science to shatter popularly perceived myths about drug use.

As all forms of drug use (legal, illicit, over-the-counter, prescription) have been shown repeatedly to influence sleep and wake schedules in people of all ages, SHC appreciates the opportunity to showcase how some of the more popular habits and substances coveted (and easily accessed) by teens can contribute to ongoing poor sleep patterns and sleep deprivation. Bad habits that take root during adolescence can set the stage for a lifetime of poor sleep and the chronic health problems that result.

Illegal drugs and their health impacts are best covered here at the NDAFW website.

Caffeine 
By far the most common drug of choice among teens, caffeine is so easily accessible and socially acceptable that it's no wonder our kids rely on it to keep them awake during the day. As adults, we provide a bad example by following this same regimen daily, forgetting that caffeine is a drug, and one that can become habituated.

The problem for teens is specific: they should not be so sleep deprived that they require a caffeine kick throughout the day to keep them awake, but early school start times make it impossible for them to get enough sleep. 

Teens who attend school districts where start times are early have been imprisoned by a system that does not understand that their sleep phases naturally run later. As a result, teens who naturally find 1 am a normal bedtime are still facing a daily rude awakening when the alarm goes off at 6 or 7am in conjunction with an earlier start time then their brains are physiologically unprepared for normal waking function.
If you'd like to petition for your local school district
to adjust bell times to accommodate the needs
of teens, contact Start School Later. They have
chapters nationwide.

Teens need at least 7 hours of sleep at night, every night, to be well rested, and those long weekend sleep-ins are no solution to the constant sleep debt they accrue.

Hence, kids with super-early schedules (either they have early school or before-school sports practices, well before the sun has even risen) are hitting Starbucks or the grocery store for a caffeinated beverage like Red Bull to jumpstart their brains artificially.

Caffeine can temporarily improve alertness by blocking sleep-related brain chemicals while jacking up adrenaline production.When the caffeine is metabolized, the brain and body hit a period of "crash" (or withdrawal), which leads to more sleepiness. need to consume more caffeine to avoid it.

Meanwhile, unless they are drinking ample amounts of water, their bodies are dehydrating, further leading to excessive daytime sleepiness. Caffeine, remember, is an addictive drug, even if it's available to anyone who wants it. Caffeine addiction leads to insomnia and general alertness at improper times of the day, typically after the sun goes down when the body and brain are supposed to be preparing for sleep.

A vicious cycle develops when teens wake up exhausted, consume regular amounts of caffeine all day long, struggle to fall asleep or sleep poorly because of caffeine's side effects, then wake up too early the next day and start the process all over again.

Caffeine does not and cannot replace sleep, and it should not be consumed after mid-afternoon by anyone who wants to achieve a normal bedtime schedule.

Parents may feel they cannot control their teens' caffeine consumption but, as with any drug, they should have fact-based discussions about using it as a way to offset sleep problems (insomnia at night, excessive sleepiness during the day) so they can be reminded that they are relying on a drug and that reliance can have long-term health consequences.

Smart drugs
Teens feel just as much, if not more, pressure these days to excel in school as their parents did back in the day. The desire to succeed academically is fueled by the idea that if they don't do well in school, they will not be able to find a good-paying job and risk living their adult lives with untenable economic instability. The job market itself has not been friendly to high school or college grads for a while, which only makes matters worse.

Controlled substances like Ritalin
are easy to find on the Internet.
The promise of better academic success by using so-called "performance" drugs becomes instantly alluring to these teens. The drugs most commonly used to improve alertness and mental vigilance are Ritalin (methylphenidate), Adderal (dextroamphetamine), and the latest popular "smart" drugs, Provigil (modafinil) and Nuvigil (armodafinil).

These medications are intended to treat problems with attention deficit, sleep disorders (like narcolepsy, shift work or circadian rhythm disorders) or depression. However, they are quickly finding their way into the hands of teens who seek them enhance their intellectual achievements in the classroom. Whether this kind of "academic doping" is ethical is beyond the scope of this article, but suffice it to say, no drugs are risk free.

These drugs fall into pharmaceutical schedules that require they only be obtained and used via a prescription for specific uses. Still, these drugs, though meant to be hard to obtain, are easily (though not safely) sourced through the Internet or can be cobbled together from the supplies intended for other family members' health concerns.

Teens (and their college-bound cohorts) are more and more inclined to use these drugs "off label" for the purposes of fighting daytime fatigue or reenergizing during a busy week of studying. The harm with using these medications comes in the fact that they all have serious side effects and, if used inappropriately, can lead to undesirable nighttime sleep problems. Also, it's illegal to use certain drugs "off label," regardless the risks.

They can also be addicting and can lead to troublesome issues with withdrawal after bingeing on them for several days in a row, all of which can disrupt circadian functions and sleep patterns in the long term.

Prescription sleeping pills 
Ambien (zolpidem tartrate)

Teens may struggle to fall asleep at night for any number of reasons; they often seek out prescription medications to help bring sleep onset. These can also be easily acquired through the Internet or by "borrowing" from other family members who use them.

By and large, the most common forms are the "Z" class drugs--zolpidem (Ambien), eszoplicone (Lunesta) and zaleplon (Sonata). These nonbenzodiazepine drugs have similar effects as their "benzo" cousins. The "Z" class drugs are meant to be used in the short term but are often used nightly; this leads to habituation, and a need for more of the drug to achieve the same affect.

Addiction is common with these drugs (see John Stamos' recent disclosure about his Ambien addiction); even without addiction as a possible outcome, bizarre behaviors, daytime "hangovers," memory issues and problems with drowsy driving are all problematic for prescription sleeping pills.

Many researchers believe a
3mg dose of melatonin
is all that's needed to
achieve a benefit
, but
people routinely use
much larger amounts
without considering safety. 
Melatonin
Despite it's easy access at nearly any drugstore, and affordability, not enough is known about this nutritional supplement to support the idea that it can help with sleep problems. Parents pop melatonin
like candy at night without remembering that, even if it's a nutritional supplement, it's also a substance with limited research into its safety and efficacy.

But because it is a supplement, it is not regulated like other sleep drugs. Also, since it's considered GRAS (generally recognized as safe), most people--including teens--decide that if a little works, a lot will work better.

But recent research has show that melatonin may have more problems with higher dosing than we first thought. 

Also, it's critical to remember that research studies almost always focus on adults and not on children or adolescents, who we now know have very different brain chemistry processes. Teenagers, for instance, have much more melatonin in their bloodstream than adults do at sunrise. Concerns about melatonin use have become a case of not knowing our own circadian systems well enough to know how much to take, and when, and whether it's even necessary.

And speaking of necessity... The practice of taking melatonin to improve sleep at night might be covering up for a separate sleep hygiene habit which could be at the crux of a teen's insomnia issues: the use of cell phones at night. 

It's not just cell phones that emit blue
spectrum light, but nearly any electronic
device with a backlit screen.
Nighttime use of cell phones (or any electronics with backlit screens that exude blue spectrum light) has major consequences for this age group.  The blue light beaming off these screens is perceived through the eye, then carried into the brain (specifically, to the pineal gland), which "reads" the light as an indication that it is daylight; this shuts down the body's own ability to generate it's own melatonin, which is necessary to fall asleep.

There are screen filters and blue-blocking glasses now available for nighttime users of electronics to help keep blue light from interfering with the normal circadian process of melatonin release at night, but the best approach is to put the screen object away at least an hour before bedtime to allow the brain to set itself and the body up for sleep. Cell phone use (games, texting, social networks) can be habit-forming, stimulating and interruptive, besides. Turning them off is perhaps the only way some teens will achieve quality sleep at night.

In doing so, teens may discover they don't need to supplement with melatonin after all, as their own brains should be making adequate amounts, given the proper opportunity. And let's face it, taking a melatonin supplement while staring at an unfiltered electronic screen more or less negates the supplement anyway.

If you are a parent of a teen, or you are a teen, and you're reading this article, please think very carefully about the impacts that these drugs can have on sleep cycles.

Diagram from Sleep Assist
Sleep is a key foundational part of the Three Pillars of Health--as critical to physical and mental health as healthy diet and regular exercise. If you take substances in order to stay awake or to fall asleep, you might want to think about why you are so sleepy (or not sleepy) to begin with.

The root cause of sleep and alertness problems is generally something more systemic that requires attention from a medical professional.

By using drugs to enhance either process, you run the risk of suffering side effects, swapping one set of problems for another, or negatively impacting your circadian rhythms in a way that could be very hard to fix in the long run.

15 January 2016

This week's sleep news, Jan 7 - 14



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 SPECIAL  || Recalls, special announcements, breaking news, events


Jack & Julie Narcolepsy Scholarship application process now open. Project Sleep’s Jack & Julie Narcolepsy Scholarship is a national effort to support students with narcolepsy and to raise awareness about narcolepsy in high school and college. From their website: "In 2016, Project Sleep will award 5 scholarships of $1,000 each to high school seniors who will attend a 4-year university and who exemplify courage and hope while living with narcolepsy. Applications are due April 1, 2016." Apply here 

Of interest to Westport CT seniors: On Thurs Jan 21 at 1:15pm, Dr. Stasia Wieber presents “Normal Adult Sleep and 5 Common Sleep Disorders” at the Westport Center for Senior Activities at 21 Imperial Avenue. Topics to cover include the importance of sleep, snoring, sleep apnea, insomnia and sleep deprivation. This free program, sponsored by Yale New Haven Health, requires pre-registration. More info: 203-341-5099 or visit the senior center website


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 TOP TEN  || Sleep news picks this week  newest to oldest

 CURATOR'S CHOICE 
1. JAN 14 || SLEEP REVIEW MAGAZINE
How one sleep center flags high-risk apnea patients, raises its volume, and lowers hospital readmissions
Business & Workplace
From the curator: These new models for healthcare are encouraging. 

 CURATOR'S CHOICE 
2. JAN 13 || THE VERGE
Google's self-driving cars would've hit something 13 times if not for humans: New report shows when and why test drivers have to take the wheel
Technology
From the curator: This technology is not ready for primetime, methinks.

 CURATOR'S CHOICE 
3. JAN 12 || BUZZ
Students and modafinil
Drugs
From the curator: Madness. We have to stop thinking a drug will fix human imperfection. 

 CURATOR'S CHOICE 
4. JAN 12 || NETDOCTOR
How to overcome menopause-related sleeplessness
Women
From the curator: More research like this, please. 

 CURATOR'S CHOICE 
5. JAN 11 || STANFORD CENTER FOR SLEEP SCIENCES AND MEDICINE

Medicare Regulations Are Driving a Wedge Between Obstructive Sleep Apnea Patients and Their Providers
Public Health & Safety
From the curator: Bean counters are not doctors. When will insurance step out of the way of legitimate healthcare?

 CURATOR'S CHOICE 
6. JAN 9 || THE NEW YORK TIMES
The Lark-Owl Scale: When Couples’ Sleep Patterns Diverge
Lifestyle & Hygiene
From the curator: This is some very thoughtful and educational reportage. I like the takeaway at the end.

 CURATOR'S CHOICE 
7. JAN 8 || DOCTOR'S LOUNGE
Financial Obstacles Only Partly to Blame for Low CPAP Acceptance
Therapies
From the curator: When patients don't use their therapies, doctors have to look at the full range of reasons why. 

 CURATOR'S CHOICE 
8. JAN 8 || FLAVORWIRE
Wellesley’s “Triggering” ‘Sleepwalker’ Sculpture Makes For Genuinely Meaningful Public Art
CultureFrom the curator: Sometimes art says what we can't comprehend as readers. 

 CURATOR'S CHOICE 

9. JAN 8 || THE GUARDIAN
As a medical student I’m terrified – but it’s not just my future at risk: Jeremy Hunt’s new contract is set to wreak havoc not only on today’s junior doctors, but on future inexperienced starters like myself, and our patients
Opinion
From the curator: More testimonials from the trenches, please. 

 CURATOR'S CHOICE 
10. JAN 8 || VAN WINKLE'S
The Surprising New Link Between Smoking Weed and Sleep
Marijuana
From the curator: I'm afraid the news isn't all that good for tokers.

**********
 WORLD  || International sleep news

JAN 11 || NEWS & STAR [UK]

More wanted to take part in Winter Warmth Appeal Big Sleep

JAN 11 || TIMES OF INDIA [INDIA]
Bombay HC allows special sleep aid for arrested corporator in jail

JAN 12 || CBC NEWS [CANADA]
BCIT nap room aims to help students focus on their studies: The pilot program follows in the footsteps of companies like Apple and Google

JAN 12 || DAILY MAIL [UK]
**********
 NATIONAL  || Sleep news across the U.S.

JAN 12 || THE DAILY ITEM [PA]
Police: Suspect took sleeping pill, drove

 CURATOR'S CHOICE 
JAN 12 || HARTFORD BUSINESS JOURNAL [CT]
Middlebury firm to pay $600K ‘whistleblower’ claim
From the curator: Dear consumers, this inspires a reminder: Please demand that the labs you visit are registered with the AASM and that they are using licensed RPSGTs and credentialed sleep physicians. Most sleep clinics are legit, but there are still some out there considered "fly by night." Don't give them your money.

JAN 12 || THE JOURNAL-GAZETTE [IN]

TRAA to distribute infant sleep kits

JAN 13 || GRAYSLAKE PATCH [IL]
Driver May Have Fallen Asleep at Wheel, Caused Fatal Crash: Police || Police said a Crystal Lake teen may have fallen asleep at the wheel and collided head on with the woman's car, according to media reports

JAN 14 || DAILY MAIL [NV]
Driver of bus that hit and killed woman 'was seen falling asleep at the wheel, but insisted the victim was jaywalking'

**********
 PUBLIC HEALTH & SAFETY || Community health: epidemiology, transportation, industry, education

 CURATOR'S CHOICE 
JAN 14 || JOURNAL OF CLINICAL SLEEP MEDICINE
Commercial Motor Vehicle Driver Obstructive Sleep Apnea Screening and Treatment in the United States: An Update and Recommendation Overview (abstract)From the curator: Protecting jobs is important, but so is protecting innocent people from sleepy drivers.

**********
 BUSINESS & WORKPLACE  || Workplace safety, corporate news, the business of sleep

JAN 12 || PR NEWSWIRE
Sleep Easily Launches with the Promise of Helping People Sleep Well Without Medication (press release)

JAN 13 || CRAIN'S NEW YORK BUSINESS

NYU Langone sleep lab to shutter after doctors bolt for Mount Sinai 

JAN 13 || REPORT LINKER

Global Sleep Apnea Market Outlook 2020 (abstract)

JAN 13 || SLEEP REVIEW

ResMed Acquires Inova Labs 

**********
 THE SCIENCE OF SLEEP  || Scientific research and basic sleep health resources

JAN 7 || OTORHINOLARYNGOLOGY BLOG
Somatic arousal and sleepiness/fatigue among patients with sleep-disordered breathing (abstract)

JAN 7 || SLEEP
A Randomized Controlled Trial of Continuous Positive Airway Pressure on Glucose Tolerance in Obese Patients with Obstructive Sleep Apnea (abstract)

JAN 7 || SPACE REF

Biological Clock Misalignment Affects Astronaut Sleep

JAN 8 || DOVE PRESS
Temporal tuning of daily rhythms helps advanced cancer patients and cancer survivors feel better, live better, and live longer (abstract)

JAN 9 || ADVANCED EXPERIMENTAL MEDICAL BIOLOGY
Treatment Options for Central Sleep Apnea: Comparison of Ventilator, Oxygen, and Drug Therapies (abstract)

JAN 9 || THE EXAMINER

Scientists discover new link between sleep deprivation and Alzheimer’s Disease

JAN 11 || SLEEP HEALTH
Short-term moderate sleep restriction decreases insulin sensitivity in young healthy adults (abstract)

JAN 12 || NEWS 2
2 Your Health Study connects sleep disorder with heart problems

JAN 12 || PHYSIOTHERAPY THEORY AND PRACTICE
Using near infrared light to manage symptoms associated with restless legs syndrome

JAN 13 || ARKLATEX
New study finds that central sleep apnea later develops into heart arrhythmia

JAN 13 || SLEEP REVIEW
Keratoconus Linked to Sleep Apnea

JAN 14 || SLEEP REVIEW MAGAZINE
Change of Heart: Electrophysiologists are increasingly acknowledging the link between atrial fibrillation and sleep apnea

**********
 TECHNOLOGY  || Devices and tools for diagnosing and treating sleep health issues

JAN 8 || MEDICAL NEWS TODAY
Snappy Sleep Stager system identifies gene related to shorter sleep

JAN 8 || THE VERGE
The Hush smart earplugs nearly sent me to sleep at CES

JAN 11 || C|NET
The next iPhone software update will help you sleep better 

JAN 11 || EMAIL WIRE
Conscious Choices Announces Sleep Mask With Cool Earplugs A Way To Erase Sleep Debt (press release)

JAN 14 || SOMNOSURE
SomnoSure Education Center Sleep Dentistry: The Dental Appliance as a First-Line Therapy for OSA (disclosure: this article was written by the SHC curator) 

**********
 PROCEDURES  || Inpatient, outpatient, and surgery-related discussions

JAN 14 || SLEEP-DOCTOR.com
3-Year Outcomes for Inspire Medical Upper Airway Stimulation

**********
 DRUGS  || Over the counter drugs, prescription medications, illicit substances, nutraceuticals

JAN 7 || ABC 2 NEWS

Report: Melatonin use can have side effects
Melatonin

JAN 7 || CDC - NCHS DATA BRIEF

Sleep Duration, Quality of Sleep, and Use of Sleep Medication, by Sex and Family Type, 2013–2014
Sleep aids

JAN 7 || CONSUMERIST

Melatonin Helps People Fall Asleep, But Has Potential Problems And Side Effects
Melatonin

JAN 7 || FOX 2 NOW
Study indicates sleep aids may lead to dementia
Over-the-counter sleep aids

 CURATOR'S CHOICE 
JAN 7 || MEN'S JOURNAL
Can Statins Lower Sleep Apnea Risks? What You Need to Know
Statins
From the curator: Interesting research.

JAN 10 || BUSINESS INSURANCE
Awakening to better sleep therapies: Painkillers, sedatives often not a helpful mix
Prescription drugs

JAN 11 || PROACTIVE INVESTORS
 THERAPIES  || Cognitive behavioral therapy, chronotherapy, phototherapy, complementary alternative medicine, functional medicine

JAN 8 || CHRONOBIOLOGY INTERNATIONAL
A unique, fast-forwards rotating schedule with 12-h long shifts prevents chronic sleep debt
Chronotherapy

JAN 9 || KEARNEY HUB
Inhale, exhale, relax to catch some sleep
Yoga

**********
 CULTURE  || Cultural and social expressions and discussions about sleep

JAN 7 || VAN WINKLE'S
Seven Strange, Scary Tales From Celebrity Sleepwalkers
Celebrities

JAN 12 || GEEKWIRE
Video inspired by ‘The Martian’ tackles real-life mystery: How to sleep in space
Film

JAN 13 || SCV NEWS
Princess Cruises Study Says Americans Want More Sleep
Travel

JAN 14 || OFFICIAL SITE OF THE COLUMBUS BLUE JACKETS
The Science of Naps: Yes, this is an actual story
Sports

**********
 LIFESTYLE & HYGIENE  || Helps for patients and clues for sleep self-improvement

JAN 7 || ITV NEWS
Top tips for a good night's sleep

JAN 11 || FOX 4 KC
Little things can make a big difference for those struggling to fall asleep

JAN 11 || SELF 
JAN 11 || TECH TIMES
Sleep Deprived? Some Tips To Help You Recover

JAN 11 || THOUGHTLEADERS
**********
 FAMILY  || Sleep health through the lifespan: pediatrics, womens health, family health, eldercare

JAN 8 || HEALTH AIM

Sleep: Women Are More Susceptible To Disorders
Women

JAN 8 || INTERIM HEALTHCARE

Aging may affect circadian rhythms, study finds
Aging

 CURATOR'S CHOICE 
JAN 8 || UNIVERSITY OF MICHIGAN HEALTH SYSTEM
Even children with higher IQs behave better when their sleep apnea is fixed
Kids
From the curator: It shouldn't be surprising how much better we perform during the day when we breathe well as we sleep at night.

JAN 9 || DECCAN HERALD

A good night's sleep
Kids

JAN 11 || BEHAVIORAL SLEEP MEDICINE

Mandatory Nap Times and Group Napping Patterns in Child Care: An Observational Study
Preschoolers

 CURATOR'S CHOICE 

JAN 11 || PARADE
Miles Brown Wants Kids to Get a Good Night’s Sleep
Kids
From the curator: Gotta love this kid!
JAN 11 || PHILLY.com
Battling alarming trend among teens: Lack of sleep
Teens

JAN 12 || THE HEALTH SITE

How much sleep do you need during pregnancy?
Pregnancy

JAN 12 || PSYCHOGERIATRICS
Rapid eye movement sleep without atonia may help diagnose Lewy body disease in middle-aged and older patients with somatic symptom disorder
Elderly

JAN 12 || SOMNOSURE
The Relationship Between Low Testosterone and Sleep Apnea: Reasons, Risks, & Treatments (disclosure: this article was written by the SHC curator) 
Men

JAN 14 || WESTERN DAILY PRESS
Disturbed sleep with frequent waking up in the elderly could be a sign of stroke
Elderly

**********
 MULTIMEDIA  || Sleep health education and issues captured in graphics, photos, audio, film

 CURATOR'S CHOICE 
JAN 12 || FOX 16
Ask the Doctor: Sleep apnea and sore throats
TV news video
From the curator: And if not sleep apnea, then UARS. Either way, it needs to be fixed before long-term problems develop.

JAN 12 || HEALTH CENTRAL
Five Signs You're a True Insomniac
Slide show

JAN 12 || WABI TV

Healthy Living: Seasonal Affective Disorder – Identification and Treatment
TV news video

JAN 14 || DAILY MAIL
Night terrors causes woman to scream until woken from sleep
TV news video

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 FIRST PERSON  || Individual accounts of living with sleep disorders

 CURATOR'S CHOICE 
JAN 9 || GIZMODO
The Deadly Reality Of Living With Sleep Apnea
Commentary
From the curator: Deadly in multiple ways. Sleep is a systemic process, people. Lack of it has an impact on all the body's systems. Untreated sleep apnea is an invitation to cut one's life short every night they go to bed. 

 CURATOR'S CHOICE 
JAN 9 || HUFFINGTON POST SLEEP + WELLNESS
Here's What Happened When I Slept For An Extra Hour Each Night
Personal experiment
From the curator: I'd love to hear more of these stories from readers. 

JAN 11 || CLINICAL ADVISOR

Quantity of sleep continues to decline in Americans
Column

JAN 13 || APPEAL-DEMOCRAT
Dear Abby: Addicted to Ambien
Advice column

 CURATOR'S CHOICE 
JAN 13 || THE PHILLIPINE STAR
Where psycho cabbies come from
Opinion
From the curator: This certainly makes me rethink the use of cabs.

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 DREAM LIFE  || The art and science of dreaming

JAN 7 || YAHOO! TECH

These sensor-studded headphones can sense when you’re in deep sleep, trigger lucid dreams

JAN 12 || VAN WINKLE'S
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The next news curation will be published on Friday January 22 2016

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